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Effect of aerobic or resistance exercise, or both, on intermuscular and visceral fat and physical and metabolic function in older adults with obesity while dieting

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Specifically, under HFD conditions, SLC25A1 inhibition promoted FAO by deacetylating carnitine palmitoyltransferase 1A and reduced glucose oxidative catabolism by triggering the acetylation-induced inactivation of pyruvate dehydrogenase E1, which caused enhanced glucose uptake and storage in the liver, and activated the SIRT1/PGC1 pathway to enhance oxidative phosphorylation for energy production

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#11885, Gibco/Thermo Fisher), penicillin, streptomycin, and 5% FBS