In fact, transgenic mice overexpressing NGF display elevated GSH concentrations in the plasma, brain, and liver ( Here, we document that a systemic reduction of GSH levels, up-regulates the transcription of L-cys/L-cys 2 and glutamate AA transporters and antioxidant genes in the striatum trough the TrkA/Akt pathway, which was mediated, at least in part, by peripheral NGF levels
P., Stylianopoulos, T., Martin, J
The quantum yield of RT-GSH is as high as 86%, which is 146-fold of that of ThiolQuant Green (Table 1)
Goal: Support cognitive function, attention, and neuroprotective pathways studied in clinical literature [2] [5]
Catalase activity increases for hydrogen peroxide breakdown, and total glutathione levels rise, creating stronger hydroxyl radical quenching capacity than glutathione alone