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It acts more like a system-wide signal touching multiple pathways at once, which is part of why its effects are so broad and, honestly, a bit unusual for something this small

What this article covers: Why GLP-1 Patches Are Trending Do GLP-1 Patches Actually Work

N Engl J Med 2021;385:503-515

injections of 100 nmol kg 1 PYY analogue ( n = 7 mice and n = 6 cages), 100 nmol kg 1 PYYMK-801 ( n = 7 mice and n = 4 cages), 100 nmol kg 1 GLP-1MK-801 ( n = 7 mice and n = 5 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) for 6 days