These results are interesting, but almost all of them come from studies on rats and mice not people
Although the magnitude of the A 1c change is small, it is consistent with the expectations for antidiabetic agents administered to subjects having excellent baseline control, and is similar to what has been observed in previous clinical trials evaluating antidiabetic agents (39)
however, there is no long-term data
A 2019 safety review examined 87 human studies on natural astaxanthin including 35 using doses of 12mg per day or higher and found no significant safety concerns or consistent adverse effects.11 Across those trials, approved or studied doses commonly ranged between 2mg and 24mg per day, and higher short-term doses (up to 40mg per day for several weeks) have also shown good tolerability in adults, with no serious events reported
de Oliveira B, Oliveira BC, Deutsch G, Pessanha FS, Thire R, de Castilho SR