does tirzepatide have cardiovascular benefits effects of which glp-1 is best for

They can both potentially result in side effects such as nausea, vomiting, diarrhea, stomach pain, constipation, discomfort, flatulence, and weight loss

In agreement with expectations, the first outcome trial of a GLP-1RA, the ELIXA trial of the short-acting lixisenatide, an exendin-4 derivative with properties almost identical to those of exendin-4 or exenatide (stable, full agonists of the GLP-1 receptor), showed no increased cardiovascular risk in a patient group with severely increased CVD risk

Tirzepatides dual receptor action produces powerful appetite suppression but can cause more initial nausea than single-agonist approaches

Sampson et al., 2016

Bowel Habits and the Association With Uremic Toxins in Non-Dialysis-Dependent Chronic Kidney Disease Patients