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If weight loss plateaus or is less than expected after 3-4 months at the maintenance dose, clinicians should reassess adherence, evaluate for medication interactions, and reinforce lifestyle modifications

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Even as millions of Americans have turned to GLP-1 drugs like Ozempic and Mounjaro which suppress appetite, thus leading to weight loss much of the conversation around personal use remains shrouded in secrecy and shame

GLP-1 receptor agonists also have favourable effects on albuminuria and may slow eGFR decline , though the evidence for hard renal outcomes is less robust than for SGLT2 inhibitors