"This portfolio of publications, derived from three major trials, significantly advances our understanding of the wide-ranging benefits of GLP-1 agonists, while also highlighting key questions that remain," said JACC Editor-in-Chief Harlan Krumholz, MD, SM, FACC
Since tirzepatide typically produces greater weight loss (20-25% body weight versus 15-17% with semaglutide at weight loss doses), more tirzepatide users may experience telogen effluvium simply because they lost more weight faster
Weight loss observed in patients using Semaglutide is not merely a side effect but a direct result of its action on appetite regulation centers in the brain
STEP UP trial (NCT05646706)
This hormone helps signal to your brain that youre full, slows how quickly food leaves your stomach, and stimulates insulin release when blood sugar rises