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CMs) may be required to parse the cell-specific role of this cAMP-generating pathway in IRI, with the lack of GLP-1(2836) responses in sAC / caSMCs providing a strong rationale

Lancet 398 , 21602172 (2021)

While studies in mice indicate the potential direct benefits of GLP-1 on the skeletal muscle and bone, human data supporting this hypothesis are absent owing to the absence of GLP-1 receptors in the human skeletal muscle, implying that any effects on muscles are likely indirect [114]

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