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Those changes come from the mechanism itself: glucose-dependent stimulation of insulin secretion, suppression of glucagon secretion, and a minor delay in early postprandial gastric emptying that reduces the rate at which glucose from a meal appears in the circulation

This works with the medications mechanism of slowing digestion rather than fighting against it

This means the drug could lose strength or become unsafe to use

For instance, if someone feels very sleepy from Benadryl, they might not notice signs of low blood sugar (hypoglycemia) like dizziness or confusion

Like the Ov GST1, FhGST-S1 does not have this Trp residue and therefore has a longer 4, although the FhGST-S1 helix aligns better to that of the mammalian PGDSs (Fig