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Jan lost 28kg (more than four stone)

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Common side effects of tirzepatide include nausea, vomiting, diarrhea, constipation, abdominal pain, decreased appetite, injection site reactions (such as redness, swelling, or pain), fatigue, and gastrointestinal issues like heartburn, gas, and bloating

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For liver histology, tissue was fixed in 10% neutral buffered formalin for 24 hours and transferred to 70% ethanol before paraffin embedding and Picrosirius red staining

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Seek medical advice if you cannot keep fluids down, develop signs of dehydration or have persistent severe abdominal pain

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