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These results show that GLP-1RA can induce phosphorylated AMPK expression (91), inhibit the expression and phosphorylation of the mTOR protein (92), promote the apoptosis of endometrial cancer cells, and thus play a potential anticancer role

Clinical Background BPC-157 was introduced in 1993 and initially studied as a potential treatment for inflammatory bowel disease due to its anti-ulcer effects

Study limitations include the high heterogeneity of study characteristics which makes it difficult to reach any strong conclusions

Rare cases of hepatic fibrosis have been reported, particularly in patients consuming alcohol, which enhances the drugs conversion to etretinate, a more hepatotoxic metabolite

Abdullah 2013