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It operates by imitating the function of the GLP-1 hormone in the body, which aids in regulating blood sugar levels, managing appetite, and fostering a sense of satiety

They are unlikely to improve with prolonged use, says Fishman

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A controlled trial that included 90 subjects with NAFLD found those treated with 303 mg silibinin along with 10 mcg (400 IU) vitamin D and 15 mg vitamin E, twice daily for six months, were more likely to improve with regard to metabolic markers, oxidative stress, endothelial function, and NAFLD progression compared with those who were untreated

Farhadi M, Salem MM, Asghari A, Daneshi A, Mirsalehi M, Mahmoudian S