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Jimmy Gutman The science of glutathione deficiency and viral infections such as COVID-19 from MedCram Figure 1

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Mechanistically, GLPs exert renoprotective effects by suppressing the PI3K/Akt/mTOR signaling cascade, promoting autophagicevidenced by increased Beclin-1 expression and LC3-II/LC3-I ratio, along with decreased p62 accumulationwhile simultaneously attenuating apoptotic activity (reducing caspase-3 and caspase-9 levels) and dampening pro-inflammatory responses (lowering IL-6, IL-1, and TNF-)

Antioxidants can be found in a number of healthy foods and can also be taken as supplements

The statistical analyses were conducted using GraphPad Prism 9.0 (GraphPad Software, CA, USA), and the ShapiroWilk test was employed to check for normal data distribution