Proceedings of the National Academy of Sciences of the United States of America 2019;116, 22624-22634, doi:10.1073/pnas.1915905116
There are many active substances that can affect the excretion of water and sodium in the kidneys, including BNP, anti-diuretic hormone, and aldosterone
CharpentierJWagetAKloppPMagnanCCruciani-GuglielmacciCLeeSJet al
For example: Gilberts syndrome , which causes mild jaundice from time to time, Hemochromatosis , which leads to iron buildup in the liver, Alpha-1 antitrypsin deficiency , which can cause liver disease
This review synthesizes current knowledge on HT's epidemiology, pathogenesis, and recent therapeutic advances, highlighting the complex interplay of genetic, environmental, and immunological factors that contribute to the disease's progression and management