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Expert analysis of GLP-1 vs dual GLP-1/glucagon therapy options

Some patients at maintenance doses with lower-concentration vials need to split their dose across two injections

And in the brain, it crosses the blood-brain barrier and activates anorexigenic neurons in the hypothalamus, specifically the POMC/CART pathways that signal fullness while suppressing the NPY/AgRP pathways that drive hunger

You can switch between GLP-1 medications if you experience intolerable side effects with the current medication, do not achieve desired outcomes despite dose adjustments, or the medication is unavailable

It can also be used for weight loss in combination with other drugs