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Subcutaneous injection ensures the compound saturates the entire system, allowing it to find and act upon receptor sites far from the administration point

Most of the observed correlations at baseline disappeared after 4 months on niacin treatment (Fig

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The discrepancy between peripheral and central administration of PYY on food intake has not been explained, but Batterham et al (72) proposed that it may be due to the activation by this peptide of Y2 receptors in hypothalamic ARC neurons where the blood-brain barrier is relatively permeable

Special considerations for specific peptides Different peptides have unique injection quirks