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GLP-1 binds the G-protein-coupled GLP-1 receptor (GLP-1R) on -cells, activating cAMP/PKA and Epac2

Clinical trials have demonstrated that certain GLP-1 receptor agonists reduce the risk of major adverse cardiovascular events in patients with type 2 diabetes and established cardiovascular disease

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Prescribe FARXIGA to help adults with HF LIVE LONGER, WITH BETTER OUTCOMES by reducing the risk of CV death and hHF 1-3 * *Also includes urgent visits for HF