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Mechanism: GLP-1 receptor agonist

This directly complicates patient screening and enrollment, leads to substantially lower overall expected efficacy compared with patients harboring upstream genetic defects (such as POMC deficiency) [56] , and results in a low statistical success rate in large-scale trials

A Dual-Action Approach to Inflammation and Metabolic Health These results add to growing evidence that metabolic health and autoimmune disease activity are closely linked