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Patients should monitor for signs of hypoglycemia (shakiness, sweating, confusion) if combining these medications with insulin or other diabetes drugs, as the additive glucose-lowering effect can create risk

GLP-1 receptor agonists work by mimicking the action of endogenous GLP-1, a hormone that stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and promotes satiety through central nervous system pathways

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