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Stress also amplifies pain perception, creating a feedback loop that perpetuates suffering

Origin, Structure and Discovery BPC-157 was first isolated and characterised from human gastric juice in the early 1990s by researchers investigating naturally occurring protective compounds in the stomach lining

Critical limitations identified in the systematic review include predominant use of small rodent models (primarily rats), short follow-up periods relative to human healing timelines, variable dosing regimens complicating dose-response assessment, and lack of standardized outcome measures across studies