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What STEP-1 Showed: Semaglutide's Impact on Lean Mass In the STEP-1 trial, participants on semaglutide 2.4 mg per week lost approximately 15% of total body weight over 68 weeks

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39 Semaglutide and Stroke Reduction SUSTAIN-6, powered for noninferiority, randomized 3297 individuals with T2DM and either established CVD or 1 cardiovascular risk factor to semaglutide 0.5 mg, semaglutide 1.0 mg or placebo (all QW subcutaneous) and followed them for a median of 2.1 years