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For women specifically, understanding how tirzepatide affects menstrual cycles is important, as hormonal shifts during rapid weight loss can alter cycle regularity

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In one trial, patients with obesity lost an average of 17.5% of their initial weight after roughly half a year of treatment

Liver Tests In a pediatric clinical trial for weight reduction, increases in alanine aminotransferase (ALT) greater than or equal to 5 times the ULN were observed in 4 (3%) WEGOVY-treated patients compared with 0% of placebotreated patients