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First, Alzheimers disease and other dementias are strongly linked to metabolic dysfunctionespecially insulin resistance in the brain, sometimes labeled type 3 diabetes. Second, a class of diabetes and weight-management medicines called GLP-1 receptor agonists (GLP-1 RAs) shows early but increasingly consistent signals that they may lower dementia risk in people with type 2 diabetes, and possibly slow specific biological changes of Alzheimers in small clinical trials

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A total of 2 10 6 cells were lysed in 250 l of IP buffer, and protein A/G beads (Yeasen) were preincubated at 4 C for 4 h to prevent nonspecific binding

[DOI] [PubMed] [Google Scholar] 22.Bredenoord AJ, Weusten BL, Timmer R, Smout AJ