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Figure 3 In the CNS, dysbiosis directly or indirectly modulates the function of microglia and astrocytes via metabolites including SCFAs

Cys 2 ), cystine-free (Cys 2 -free), or cystine-free/GSH-supplemented (750 M) medium for the indicated timepoints, and cell numbers were determined (n = 2 technical replicates representative of one experiment)

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The ongoing Phase 3 programme known as the TRIUMPH trials is evaluating retatrutide across a broader population, including individuals with obesity, type 2 diabetes, and cardiovascular risk factors

Degraded peptides won't work