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In addition, HDACi promotes the degradation of ECM by regulating the activity of matrix metalloproteinases (MMPs), thereby attenuating the interaction between tumor cells and the stroma and further inhibiting tumor metastasis ( 2.2 Effect of HDACi on macrophages The role of HDACi in regulating the tumor microenvironment is receiving increasing attention, particularly its impact on tumor-associated macrophages

Monitor blood sugar if diabetic, as hypoglycemia can cause both headaches and dizziness

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Pointing out these problems, some experts pointed out that the new treatment is not appropriate for the Korean treatment standard suited for overweight patients with a BMI of 30kg/ or more with a BMI of 27kg/ or more, having one or more weight-related comorbidities