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: Li J, Liu L, Weng J, Yin TL, Yang J, Feng HL

Many individuals discontinue treatment when weight loss plateaus, assuming that the medication is no longer providing value

"Pentadecapeptide BPC 157 (PL-10) promotes tendons-to-bone healing in a rat model of rotator cuff repair." J Orthop Surg Res

This occurs because the underlying biological drivers of obesity, hormonal setpoints, metabolic adaptation, and appetite regulation, reassert themselves once the pharmacological intervention is removed