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And in 2024, after conducting a systematic review and GRADE analysis on the topic, the Society of Obstetricians and Gynecologists of Canada (SOGC) updated their Clinical Practice Guidelines to reflect the evolution of the evidence, stating (7,8): Regardless of the type of exposure, RhIG is not recommended 20 weeks = 300 mcg plus , depending on your local institution/lab, you will then either order the screening Rosette test or the definitive Kleihauer-Betke test to determine if more is required The Rosette test is a sensitive, qualitative screening test for feto-maternal hemorrhage

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