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This theory is supported by the clinical data showing that tirzepatide produces comparable appetite suppression with less severe gastric emptying delay

[1] [2] While these medications offer significant therapeutic benefits, fatigue is a side effect that some people experience, which can affect daily functioning and quality of life

Medical News Today, 2026

Novos next-gen obesity asset came out worse

Mean baseline HbA1c was 7.83% and 7.80%, and baseline BMI was broadly comparable across included trials, with mean values of approximately 33.3 kg/m 2 for semaglutide and 33.6 kg/m 2 for tirzepatide, and an overall range of approximately 31 to 36 kg/m 2