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Inflammation of the pancreas (pancreatitis)

Pharmaceutical GLP-1 agonists produce sustained receptor activation at levels far exceeding what natural GLP-1 achieves, even after meals

There is a steadily growing demand for weight loss medications

GLP-1 stimulates the secretion of insulin , a hormone responsible for decreasing blood sugar, and inhibits the release of glucagon, a hormone that increases blood sugar levels

GLP-1s are not FDA-approved for use in type 1 diabetes in the U.S., however, some doctors do prescribe them off-label for patients who are overweight and struggle to achieve glycemic goals with insulin alone