Hoon MW, Johnson NA, Chapman PG, Burke LM
Through a structure-based virtual screening strategy, the small-molecule compound 84-B10 has been identified as a novel LONP1 activator that attenuates renal fibrosis and mitochondrial dysfunction [127] (Fig
However, semaglutide and tirzepatide will likely remain appropriate first line options for patients with less severe obesity or those who prefer established medications with longer safety track records
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