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Incident AF was the primary outcome and captured by a validated algorithm (positive predictive value 69%-77%) based on ICD version 9 code 427.3 or version 10 code I48 in at least two outpatient records within 2 years or in one inpatient record or on problem list, with the earliest date as the event date

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While we noted differential effects of BPM31510 between cell lines in pyruvate (Complex I)-driven respiration, BPM31510 significantly decreased succinate (Complex II)-driven and mGPDH-driven respiration and had no effect on Complex IV-driven responses in MIA PaCa-2 and PANC1 cells (Fig