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While gastrointestinal side effects like nausea and diarrhea are well-documented, some patients report flu-like symptoms during treatment

In August 2025, Wegovy received accelerated approval for the treatment of adults with metabolic dysfunction-associated steatohepatitis (MASH) with moderate to advanced liver scarring (fibrosis), but not with cirrhosis of the liver

You should also check in with your doctor if you notice any of the following: Your cycles are a lot shorter or longer than usual You have very heavy or very light periods Youre experiencing significant changes in premenstrual symptoms Youre getting severe cramping or pain is getting much worse Your doctor or clinician can determine if Mounjaro or another factor is causing these changes

Oral semaglutide is a novel GLP-1RA with 94% homology to human GLP-1 which is co-formulated with absorption enhancer sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC), that overcomes the challenges of peptide absorption in the acidic conditions of the stomach

These prescription weight loss drugs are especially effective for people who have struggled to lose weight through diet and exercise alone and need additional medical support