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Pseudomonas can utilize the kynurenine pathway to generate anthranilate, and then synthesize the quorum-sensing signaling molecule 2-heptyl-3-hydroxy-4-quinolone (Pseudomonas quinolone signal, PQS)

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The medication is commonly used alongside metformin, with the combination often providing complementary mechanisms of action for improved glycemic control

Weight loss at the highest dose (9 mg) reached up to 20.1%, with other doses showing dose-dependent responses (9.5% to 20%)