There are a few things to consider if levels don't rise despite supplementation
The trial exhibited a favorable safety profile with mostly mild to moderate gastrointestinal adverse events, including diarrhea (38% versus 19% in placebo), constipation (27% versus none), and appetite loss (31% versus 8%)
AAV vectors are generally safe at therapeutic doses eight AAV-based gene therapies have been FDA-approved as of 2024 but at high doses, above roughly 10^14 viral genomes per kilogram, the literature documents immune reactions, liver toxicity, and in rare cases, genotoxicity
This ensures healing tissue receives enough oxygen and nutrients while clearing waste efficiently
Zinc has been recognized in the nutrition of animals and humans, even though the evidence for an uncomplicated zinc deficiency in humans is limited