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But there was no significant difference in time to first MACE by weight loss in the first 20 weeks of the trial

In a study of 2,539 patients assigned to take either tirzepatide or placebo for 72 weeks, the average weight loss achieved for patients taking tirzepatide 5 mg was 15%

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Theyre penny-wise and pound-foolish, saving money today by denying a $50/month compounded medication, then paying $50,000 for the bypass surgery in five years