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These shifts in hydration and mineral balance contribute to headache frequency

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Additional risk factors like obesity, metabolic dysfunctions, and meal timing make nausea more likely and more severe for others

Abbreviations CI: confidence interval FDA: Food and Drug Administration FXR: farnesoid X receptor NAFLD: nonalcoholic fatty liver disease NASH: non-alcoholic steatohepatitis OCA: obeticholic acid PIVENS: pioglitazone versus vitamin E versus placebo for the treatment of nondiabetic patients with nonalcoholic steatohepatitis PPAR: peroxisome proliferator-activated receptor TONIC: treatment of NAFLD in children UDCA: ursodeoxycholic acid Declarations Funding None to declare