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In contrast, the number of interactions increases in the other six structures as the K m value decreases
Unlike the glycolysis-related enzyme HK2, the gluconeogenesis-related enzymes phosphoenolpyruvate carboxykinase 1 (PCK1) and glucose-6-phosphatase catalytic subunit (G6PC) exhibited no consistent changes, indicating no common effect on gluconeogenesis in both IEC6 and Caco-2 cells
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