It is important to consult with a healthcare professional for an accurate diagnosis and appropriate treatment plan
Int J Mol Sci 23(24):15906 Geist HJ, Laverty CG, Donkervoort S, Hu Y, Silverstein S, Neuhaus SB, Saade D, Vaughn G, Malicki D, Kaur R, Li Y, Luo Y, Liu P, Burr P, Foley AR, Mohassel P, Bnnemann CG (2024) Clinical, immunohistochemical, and genetic characterization of splice-altering biallelic DES variants: therapeutic implications
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Future studies should investigate the impact of VISTA inhibition on the metabolic reprogramming of MDSCs and its effects on proinflammatory cytokine production could provide new insights into modulating MDSC function
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