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Indian J Ophthalmol 57(4):273279 McDonald EM et al (2014) Topical antibiotics for the management of bacterial keratitis: an evidence-based review of high quality randomised controlled trials
These findings lend support to the hypothesis that the increase in SHBG levels induced by liraglutide might contribute per se to reduce the risk of developing the metabolic syndrome in PCOS, also considering the effect of SHBG in directly suppressing inflammation and lipid accumulation in macrophages and adipocytes [65]
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Probably, the low binding affinity is an artifact of the receptor isolation, as the physiologically relevant affinity of thiamine to the receptor may require proteinprotein interaction within the native structure of the synapses
In contrast, a meta-analysis of 10 randomized canagliflozin trials reported a similar incidence of UTIs between canagliflozin and placebo (RR 1.19
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