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Third, the study is unique in also using validated questionnaires for mental disorders common in obesity and T2D to standardise the baseline mental health characteristics of the participants and attempt to substantiate and further interpret the subjective experience of change in mental health with change in scores

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Moreover, cardiometabolic effects of GLP-1 are attenuated in obesity and T2D, via mechanisms that may involve impaired p38-MAPK signaling

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