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patients with severe gastrointestinal disease or gastroparesis may not be suitable candidates Hypersensitivity reactions : Including anaphylaxis, have been reported rarely Injection site reactions , including erythema, pruritus, or induration, occur in approximately 25% of patients and are generally self-limited

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The approved dosing interval is once weekly , and there is no official FDA recommendation for biweekly (every-other-week) administration as a standard maintenance regimen

The trial underscored that Retatrutide brings a promise of unprecedented effectiveness, positioning it as a viable alternative to traditional surgery