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The lack of well-designed, comprehensive, human clinical studies means that there is little to no reliable scientific evidence to support the safety or effectiveness of BPC-157 in humans

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A recent meta-analysis study reviewed twelve randomized controlled trials (RCTs) (n = 791) and found that ALC supplementation significantly reduced depressive symptoms in MDD as monotherapy and augmentation compared to placebo, with effect sizes comparable to standard antidepressants and a superior safety profile

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