At Moderate severity, watch for quinolone and tetracycline antibiotics, cephalexin, penicillamine, blood thinners like warfarin, blood pressure medications (especially losartan and ACE inhibitors), cholesterol drugs like pravastatin and atorvastatin, heart rhythm medications (verapamil, diltiazem, digoxin), anticoagulants and antiplatelet drugs, thiazide diuretics, ritonavir, integrase inhibitors, and several others
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2018 Jun 7;13(6):e0198626.
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Kojic acid typically shows initial results in 2-4 weeks, glutathione in 4-8 weeks, and alpha arbutin in 6-12 weeks