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In these pathway categories, the most highly affected pathways were valine, leucine, and isoleucine biosynthesis (Additional file 6: Figure S6)

During cellular stress, such as nutrient starvation and catabolic stress after trauma, surgery, infection, sepsis, or cancer cachexia, blood glutamine levels are severely decreased 144

En casos excepcionales, el tiempo puede extenderse hasta 5 a 7 das hbiles

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Duration of NFT-dependent increase in glutathione levels To determine the duration and the response of glutathione following withdrawal and re-addition of NFT, HepG2 cells were treated with NFT (20 M) for 48 h, followed by withdrawal of NFT for 24 h and a subsequent re-addition of NFT for an additional period of 24 h (Fig