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Retatrutide is an investigational once-weekly injectable peptide that simultaneously activates GLP-1, GIP, and glucagon receptors, distinguishing it from approved single or dual receptor agonists such as semaglutide and tirzepatide
Neither form interferes with semaglutide
GLP-1/GIP Receptor Dual Agonists Gastric inhibitory polypeptide (GIP) is a peptide hormone released by K-cells of the small intestine in response to food, which increases pancreatic insulin release
That gap between 'eats less' and 'heart disease risk drops' is what is driving the deeper scientific interest
D., Woodman, R
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