how long do side effects last with semaglutide Effects: What Patients Should Know in 2025 How Long Do Semaglutide Side

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10.1016/S1474-4422(09)70054-7 [DOI] [PMC free article] [PubMed] [Google Scholar] Dirnagl U., Meisel A

The initial phase typically follows this pattern: Short-term Response: Most patients experience diarrhea for approximately 3 days after starting Ozempic treatment Adjustment Period: Symptoms commonly persist during the first four to five weeks of treatment Gradual Improvement: Side effects typically decrease in frequency as the body adjusts Research shows that gastrointestinal side effects are noticeable when patients first start Ozempic or after a dose increase [7]