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Clinical studies most often report mild side effects, including nausea, vomiting, diarrhea, heartburn, gas, headache, and general digestive discomfort.27 A 2021 safety review of high-dose NAC in chronic respiratory diseases found that oral doses between 600mg and 3,000mg daily were generally well tolerated, with gastrointestinal symptoms reported but not consistently more often than placebo.35 That doesnt mean NAC is risk-free

Comparing their mechanisms reveals why semaglutide has demonstrated significant weight loss outcomes in clinical trials, whereas glutathione's role in weight management remains indirect and largely supportive

However, long-standing neurological deficits may become irreversible, especially if treatment is delayed [31]

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