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Results Both G protein and arrestin pathways of GLP-1R can be activated by N-terminally truncated GLP-1 or EX4 that are fused to the receptor Peptide hormones are agonists of class B GPCRs that induce the receptors to recruit either stimulatory G proteins (Gs), leading to elevation in intracellular cAMP levels, or G protein-coupled receptor kinases for receptor phosphorylation, leading to arrestin recruitment and arrestin-mediated pathways

Hydrogen peroxideproduction, fate and role in redox signaling of tumor cells

& Herrero, L

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the presence of hypertension, ischemic heart disease, heart failure, proteinuria or diabetes complications