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In a direct head-to-head comparison, tirzepatide demonstrated similar benefits in reducing MACE as semaglutide

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If needed, unused pens may be kept at room temperature (up to 86F or 30C) for up to 21 days

Furthermore, it is being investigated for its potential use in chronic weight management, reducing the risk of major adverse cardiovascular events, and managing other conditions such as heart failure with preserved ejection fraction, obesity, and non-cirrhotic non-alcoholic steatohepatitis.The Phase 3 SURPASS 1-5 clinical trial program was conducted to evaluate the safety and effectiveness of tirzepatide, which was administered once weekly through subcutaneous injections at different doses (5, 10, and 15 mg)