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Furthermore, in three previous RCTs of non-pregnant hypertensive patients, with and without CVD, we demonstrated that intervention with low-dose riboflavin (16 mg/d) for 16 weeks resulted in a lowering of systolic blood pressure by up to 13 mmHg, specifically in those with the TT genotype (Reference Horigan, McNulty and Ward112Reference Wilson, Mcnulty and Ward114)

This robust approach to logistics ensures that every vial maintains its peak potency for reliable research outcomes

However, the bioavailability of the antioxidants was not measured in these animals

73.5% reached HbA1c 6.5% vs 15.9% placebo